Saturday, March 31, 2018
  BIG finding

This is a BIG finding!
First author Anish Mitra, PhD, and Andrew Kraft, PhD – both MD/PhD students at Washington University – and colleagues decided to approach the mystery of the ultra-slow waves using two techniques that directly measure electrical activity in mice brains. In one, they measured such activity on the cellular level. In the other, they measured electrical activity layer by layer along the outer surface of the brain.

They found that the waves were no artifact: Ultra-slow waves were seen regardless of the technique, and they were not the sum of all the faster electrical activity in the brain.

Instead, the researchers found that the ultra-slow waves spontaneously started in a deep layer of mice’s brains and spread in a predictable trajectory. As the waves passed through each area of the brain, they enhanced the electrical activity there. Neurons fired more enthusiastically when a wave was in the vicinity.

Moreover, the ultra-slow waves persisted when the mice were put under general anesthesia, but with the direction of the waves reversed.
Nothing new about the existence of slow waves in the brain. Known as long as EEG has been around. The BIG part is the triggering or polling effect (enhancing electrical activity), and the BIGGEST part is the reversal when unconscious.

How do senses come in to awareness and memory? Vision and hearing are processed first in a complex series of filtering centers in the brainstem. The resulting CODED signals describing movements of colors and shapes, and movements of frequencies and intensities, are then sent out to the cortex for high level comparison to memory templates. Match the formants with intonation, phonemes, morphemes, and grammar. The results of the match are then stored in memory for use in the next comparison.

The outward polling would enhance or speed the movement of coded data from brainstem out to cortex.

What happens when the polling shifts into reverse? Memories and patterns from the cortex flow better toward the centers of awareness in the brainstem, where they are treated as sensory data. DREAMS.


= = = = =

Later thought: The radial fibers (corona radiata) of the white matter wouldh't care much about this outward-moving stimulation. They are essentially wires from the cortex to the brainstem. The passage of charge waves might help to encourage flow of ions, especially on the part of the axon inside the myelin, which is a candidate for subconscious or dreamy action.

The charge waves would have their best effect on the association fibers that tie various parts of the radial fibers together permanently or temporarily, creating patterns and templates. You can imagine them being activated in sequence:



If we think about polling or scanning, the waves would be similar to sonar or radar, multiplexing different types of association into a time series. With normal sonar (bat or electronic) the sender calculates location of an object by the time between sent pulse and received pulse. In this type of scan the sender would be activating the various circumferential associations in sequence, and picking up the sequential results in the radial fibers. Maybe a better analogy would be the old acoustic delay line computer memories.

= = = = =

I went ahead and bought the full paper. For once the paid part contains more info than the abstract. Usually you don't get extra by paying. The first thing that stands out: In the mouse, each complete scan is about 10 seconds, though the wave as observed by experimental methods is not strongly periodic. This is much slower than breathing or heartbeat or motor response time. It's suggestively close to minimal attention span, which is 7 seconds in humans. We can be trained to hold attention longer, but TV producers know how to lock in phase with the 7 second basic span.

Labels:

 


<< Home

blogger hit counter
My Photo
Name:
Location: Spokane

The current icon shows Polistra using a Personal Equation Machine.

My graphics products:

Free stuff at ShareCG

And some leftovers here.

ARCHIVES
March 2005 / April 2005 / May 2005 / June 2005 / July 2005 / August 2005 / September 2005 / October 2005 / November 2005 / December 2005 / January 2006 / February 2006 / March 2006 / April 2006 / May 2006 / June 2006 / July 2006 / August 2006 / September 2006 / October 2006 / November 2006 / December 2006 / January 2007 / February 2007 / March 2007 / April 2007 / May 2007 / June 2007 / July 2007 / August 2007 / September 2007 / October 2007 / November 2007 / December 2007 / January 2008 / February 2008 / March 2008 / April 2008 / May 2008 / June 2008 / July 2008 / August 2008 / September 2008 / October 2008 / November 2008 / December 2008 / January 2009 / February 2009 / March 2009 / April 2009 / May 2009 / June 2009 / July 2009 / August 2009 / September 2009 / October 2009 / November 2009 / December 2009 / January 2010 / February 2010 / March 2010 / April 2010 / May 2010 / June 2010 / July 2010 / August 2010 / September 2010 / October 2010 / November 2010 / December 2010 / January 2011 / February 2011 / March 2011 / April 2011 / May 2011 / June 2011 / July 2011 / August 2011 / September 2011 / October 2011 / November 2011 / December 2011 / January 2012 / February 2012 / March 2012 / April 2012 / May 2012 / June 2012 / July 2012 / August 2012 / September 2012 / October 2012 / November 2012 / December 2012 / January 2013 / February 2013 / March 2013 / April 2013 / May 2013 / June 2013 / July 2013 / August 2013 / September 2013 / October 2013 / November 2013 / December 2013 / January 2014 / February 2014 / March 2014 / April 2014 / May 2014 / June 2014 / July 2014 / August 2014 / September 2014 / October 2014 / November 2014 / December 2014 / January 2015 / February 2015 / March 2015 / April 2015 / May 2015 / June 2015 / July 2015 / August 2015 / September 2015 / October 2015 / November 2015 / December 2015 / January 2016 / February 2016 / March 2016 / April 2016 / May 2016 / June 2016 / July 2016 / August 2016 / September 2016 / October 2016 / November 2016 / December 2016 / January 2017 / February 2017 / March 2017 / April 2017 / May 2017 / June 2017 / July 2017 / August 2017 / September 2017 / October 2017 / November 2017 / December 2017 / January 2018 / February 2018 / March 2018 / April 2018 / May 2018 / June 2018 / July 2018 / August 2018 / September 2018 / October 2018 / November 2018 / December 2018 / January 2019 / February 2019 / March 2019 / April 2019 / May 2019 / June 2019 / July 2019 / August 2019 / September 2019 / October 2019 / November 2019 / December 2019 / January 2020 / February 2020 / March 2020 / April 2020 / May 2020 / June 2020 / July 2020 / August 2020 / September 2020 / October 2020 / November 2020 / December 2020 / January 2021 / February 2021 / March 2021 / April 2021 / May 2021 / June 2021 / July 2021 / August 2021 / September 2021 / October 2021 / November 2021 /


Major tags or subjects:

2000 = 1000
Carbon Cult
Carver
Constants and variables
Defensible Cases
Defensible Times
Defensible Spaces
Equipoise
Experiential education
From rights to duties
Grand Blueprint
Metrology
Natural law = Sharia law
Natural law = Soviet law
Shared Lie
Skill-estate
Trinity House
#Whole-of-society

Powered by Blogger